Review Article on Investigating the use of Medicinal Plants in Protecting Against Neurodegenerative Disease and Mental Disorder

Abstract

Neurodegeneration, the word describing the condition of neuronal death brought on by a chronic, degenerative disease, is one of the most significant health concerns of the twenty-first century. Parkinson's, Alzheimer's, epilepsy, and other neurodegenerative illnesses (NDs) and Huntington's, which affect millions of people globally, represent a serious danger to global health. The potential therapeutic effects of traditional herbal therapy in controlling and preventing certain disorders have drawn attention. Six herbal plants, including Curcuma longa (turmeric), Lavandula angustifolia (lavender), Rosmarinus officinalis (rosemary), Cardiospermum halicacabum (balloon vine), Careya arborea (wild guava), and Withania somnifera (ashwagandha), are highlighted in this review for their neuroprotective qualities. These plants have antiinflammatory, anti-apoptotic, and antioxidant properties that prevent neurodegeneration and increase neuronal survival. Their bioactive substances, including linalool, curcumin, and Withanolides show promise in reducing oxidative stress, neuroinflammation, and cognitive loss. An overview of various well-known neuroprotective plants and their therapeutic applications in the treatment of NDs is given in this review, which also highlights the pharmacological characteristics, modes of action, and current knowledge of their effectiveness.