Garlic Oil and Manuka Honey-Based Nanoemulsion Systems for Antimicrobial Therapy: Current Insights and Future Perspectives
DOI:
https://doi.org/10.62896/ijmsi.2.1.13Keywords:
Garlic oil, Manuka honey, Nanoemulsion, Antimicrobial therapy, Polyherbal formulationAbstract
Garlic oil and Manuka honey are natural antimicrobial agents widely recognized for their therapeutic potential. Garlic oil contains sulfur-based compounds responsible for antimicrobial activity, while Manuka honey exhibits unique antibacterial properties due to methylglyoxal content. However, their pharmaceutical application is limited by poor solubility, instability, and formulation challenges. Nanoemulsion-based drug delivery systems provide an effective approach to enhance stability, bioavailability, and antimicrobial efficacy. This review focuses on formulation strategies, characterization, antimicrobial mechanisms, applications, challenges, and future perspectives of garlic oil and Manuka honey-based nanoemulsion systems. The synergistic effect of these natural components makes them promising candidates for topical antimicrobial therapy, especially in acne management.


